Lipoic Acid is a vitamin-like substance naturally produced by the human body. In addition to neutralizing dangerous free radicals, Lipoic Acid is also essential for the production of cellular energy.*
R-Lipoic acid is a compact, sulfur-rich, vitamin-like molecule that is vital for energy production in all tissues. R-Lipoic acid functions as a cofactor for energy release from ATP in the mitochondria of every cell, which is essential for optimal immune activity. RLA has immune-strengthening actions in fatty or protein-rich tissues, and it binds up free radicals. It is fat-soluble, but it works well in watery tissue fluids too. As it can navigate cellular membranes throughout the body, Lipoic Acid can cross the blood-brain barrier to protect myelin, the fatty protective sheath around nerves.
Alpha Lipoic Acid consists of a 50/50 mixture of the R- (natural) and S- (unnatural) forms (enantiomers). It is the most widely available commercial form of Lipoic Acid. R-Lipoic Acid is the form of Lipoic Acid that occurs naturally in plants, animals and the body and is responsible for the specific beneficial effects of Alpha Lipoic Acid.
R-Lipoic acid is the only variant of Lipoic Acid that exists in nature and is the only effective, bio-identical form. Lipoic can be made in two isomers, the R and S forms, but R-Lipoic Acid is the sole medically active variety. Because of the difficulty and high cost of isolating natural R-Lipoic Acid, many common formulas labeled ‘Alpha Lipoic Acid’ contain a synthetic 50-50 mixture of R-Lipoic Acid and (trans) S-Lipoic acid. These R- and S-isomers are mirror images of each other, but only the R-form brings true medicinal benefits, while the S-form is relatively useless. RLA is at least ten times more potent at a cellular level.
R-Lipoic Acid (RLA), is the natural form of Lipoic Acid — the exact type the body makes and requires. RLA is significantly more potent than Alpha Lipoic because the body “recognizes” it and “knows” how to use it.
Research indicates that not only does the human body have difficulty absorbing the unnatural (S) version; it may actually inhibit the most essential properties of natural R-Lipoic Acid.
R-Lipoic Acid has powerful antioxidant functions:
Lipoic Acid is the only antioxidant that dissolves in both the fatty and watery tissues of the body, so it can protect the fatty cell membrane and the aqueous cell interior from harmful free radicals.
*R-Lipoic Acid (RLA) can also boost the activity of natural and dietary antioxidants such as glutathione, coenzyme Q10, and vitamin C, to protect healthy tissues. Lipoic Acid may reduce the aches and pains associated with aging.
RLA has powerful antioxidant functions:
It’s preferable to take R-Lipoic Acid on an empty stomach, at least 1/2 hour before a meal, or 3 hours after, preferably in the morning to early afternoon.
If you experience any nausea due to lowered blood sugar, eat lightly. The absorption will be slower with food, but the efficacy will not be affected.
R-Lipoic Acid (RLA) inhibits the over-activation of inflammatory immune system cells, helping to calm excess inflammation which could impede immune action. RLA restores and improves the optimal function of natural killer immune system cells. It reduces cell damage in intestinal walls from common microbes, protecting the essential barrier of the digestive tract lining. RLA reduces the over-production of inflammatory cytokine proteins.
RLA regulates the brain’s immune response to microbes and certain viruses. It is a potent antioxidant and it increases optimal immune activity.
Bio-Enhanced® R-Lipoic Acid is formulated using a unique stabilization process that ensures maximum absorption. Pharmacokinetic data has shown that our
Bio-Enhanced® R-Lipoic Acid products have 40x the absorption rate of unstabilized RLA.
Without special processing, R-Lipoic Acid (RLA) is highly unstable and difficult to absorb. In fact, only a small percentage of unstabilized RLA can actually be absorbed.
Plus, unstabilized RLA can also contain harmful heavy metals and residual solvents that are very difficult to remove. The processing and stabilization of GeroNova’s products removes all traces of residual solvents from the raw material.
There is no standardized definition for the term “pharmaceutical grade.” However, we manufacture our products with the utmost concern for product purity, quality, and safety.
Store products tightly sealed in a cool, dry place.
Refrigeration is not necessary.
It will vary depending on your current health, conditions you may have, and dosage. Our customers report that they feel better, and experience clearer thinking and “enhanced well being within 2-3 weeks”. For optimal results, we recommend you take our R-Lipoic Acid daily for at least two months to evaluate the benefits.
They report fewer respiratory tract infections, improvements in recurring or chronic infections, and reduced chronic degenerative symptoms in joints, eyes, or connective tissues. In addition, they experience relief from neuropathy, tinnitus, and other nerve conditions. RLA is also a valuable support nutrient for retina protection and blood sugar balance.
Our Bio-Enhanced® R-Lipoic Acid is available in two water-soluble products:
The benefit of water-soluble R-Lipoic Acid salts is that they are absorbed quickly and are therefore fast-acting.
R-Dihydrolipoic Acid is the reduced (has electrons added) form of R-Lipoic Acid.
Currently there are no established daily doses for supplementation. However, GeroNova scientists and medical advisors currently believe optimal dosing is 100-600 mg/day.
ALL Lipoic Acid comes from China, including the R form. All the starting materials also come from China. India might be a new manufacturer at some point in the future. There is no Lipoic Acid made completely in Europe or anywhere else in the world, despite erroneous claims. ‘European made’ material is not available commercially and is only produced in very small batches for research. Even this material is made with original starting material from China. The bulk material we use in our own products and sell in bulk, is produced and sourced from our sister facility China, where it is made according to our internal proprietary process and specifications.
We often say when asked this question as to where our material comes from – A molecule does not know where it is made. It is analysis and purity that ultimately makes a difference.
Our material is rigorously tested in the US before it is made into finished products in a cGMP certified, NSF facility. Many testing labs in the US also use our verified standards and methods to test almost all R-Lipoic Acid available for purchase.
All of our finished products are made in the US.