The Immunomodulatory Effect of Alpha-Lipoic Acid in Autoimmune Diseases.

May 30, 2019 Science Blog By

Αlpha-lipoic acid is a naturally occurring antioxidant in human body and has been widely used as an antioxidant clinically. Accumulating evidences suggested that α-lipoic acid might have immunomodulatory effects on both adaptive and innate immune systems. This review focuses on the evidences and potential targets involved in the immunomodulatory effects of α-lipoic acid. It highlights the fact that α-lipoic acid may have beneficial effects in autoimmune diseases once the immunomodulatory effects can be confirmed by further investigation.



  1. iomed Res Int. 2019 Mar 20;2019:8086257. doi: 10.1155/2019/8086257. eCollection 2019.
  2. Liu W, Shi LJ, Li SG..

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