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MEMORY AND BRAIN AMYLOID AND TAU EFFECTS OF CURCUMIN IN NON-DEMENTED ADULTS: A DOUBLE-BLIND, PLACEBO-CONTROLLED 18-MONTH TRIAL

Background Because the anti-inflammatory and anti-amyloid properties of curcumin could protect the brain from age-related neurodegeneration and memory decline, we studied the effects of curcumin on memory performance in non-demented adults and explored its potential impact on brain amyloid plaques and tau tangles using FDDNP-PET. Methods Forty subjects (age 51 to 84 years) were randomized […]

April 23, 2019 Science Blog By GeroNova Research

Curcumin May Reverse Memory Problems, Improve Mood

With more and more of the aging population affected by Alzheimer’s disease, and clinical trials for new medications often providing underwhelming results, a new study in The American Journal of Geriatric Psychiatry may be especially promising. It finds that taking a daily dose of curcumin, the compound in turmeric root that gives curry its yellow […]

April 23, 2019 Science Blog By GeroNova Research

Alpha lipoic acid inhibits oxidative stress-induced apoptosis by modulating of Nrf2 signalling pathway after traumatic brain injury.

Alpha lipoic acid (ALA) is a powerful antioxidant which has been widely used in the treatment of different system diseases, such as cardiovascular and cerebrovascular diseases. But, there are few studies that refer to protective effects and potential mechanisms on traumatic brain injury (TBI). This study was carried out to investigate the neuroprotective effect following […]

April 17, 2019 Science Blog By GeroNova Research

Effects of lipoic acid on walking performance, gait, and balance in secondary progressive multiple sclerosis.

BACKGROUND: Gait and balance impairment is common in secondary progressive multiple sclerosis (SPMS). Lipoic acid (LA), an over-the-counter antioxidant, is effective in MS animal models and may improve walking speed, but effects on mobility are unreported. OBJECTIVE: Examine the effects of 1200 mg daily oral dose of LA versus placebo (PLA) on gait and balance in […]

March 12, 2019 Science Blog By GeroNova Research

The effect of alpha lipoic acid on uterine wound healing after primary cesarean section: a triple-blind placebo-controlled parallel-group randomized clinical trial.

PURPOSE: To investigate the effect of alpha lipoic acid (ALA) on uterine wound healing after primary cesarean section (CS). METHODS: A parallel-group, triple-blind, placebo-controlled randomized clinical trial was conducted in Ain Shams University Maternity Hospital, Cairo, Egypt, involving 102 women undergoing pre-labor primary CS. The participants were randomly assigned using a computer-generated list of random […]

March 12, 2019 Science Blog By GeroNova Research

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