Science Blog

Lipoic Acid Therapy Found to Slow Rate of Brain Atrophy

LONDON—Treatment of patients diagnosed with progressive forms of multiple sclerosis (MS) with lipoic acid appeared to improve patients outcomes, in particular, reducing the rate of brain atrophy, researchers reported at the Congress of the European Committee for Treatment and Research in Multiple Sclerosis. In a small placebo-controlled trial, magnetic resonance imaging revealed a lower rate […]

September 18, 2016 Consumer Blog By GeroNova Research

Alpha lipoic acid attenuates high-fructose-induced pancreatic toxicity.

Abstract OBJECTIVES: Chronic consumption of high-fructose corn syrup (HFCS) causes several problems such as insulin resistance. The goal of the study was to investigate pancreatic damage induced by chronic HFCS consumption and the protective effects of alpha lipoic acid (ALA) on pancreatic cells. METHODS: Wistar Albino, 4-month-old, female rats weighing 250-300 g were randomly distributed into […]

April 19, 2016 Science Blog By GeroNova Research

Alpha-lipoic acid protects mice against concanavalin A-induced hepatitis by modulating cytokine secretion and reducing reactive oxygen species generation.

Abstract BACKGROUND: Alpha-lipoic acid (α-LA), which exits in almost all types of prokaryotic and eukaryotic cells, is a key regulator of energy metabolism in mitochondria. This study was designed to explore the protective effect of α-LA against concanavalin A (Con A)-induced hepatitis in mice and explore the potential mechanism. METHODS: Acute autoimmune hepatitis was induced […]

April 19, 2016 Science Blog By GeroNova Research

Multiple protective mechanisms of alpha-lipoic acid

A new study examined the protective effect of α-LA against H2O2-induced oxidative stress and apoptosis in human lymphoid cells. Human peripheral blood lymphocytes were preincubated with α-LA and then exposed to H2O2. After that, the viability of the cells, rate of apoptosis, oxidative stress biomarkers such as reactive oxygen species (ROS) and level of lipid […]

February 19, 2015 Science Blog By GeroNova Research

Blog Introduction

Welcome to the Lipoic Acid Science Research Blog. This blog/forum is intended for students, scientists, medical practitioners and consumers. The focus will be a review of peer reviewed papers, patents, unpublished studies, discussions of hot topics and unsolved problems in lipoic acid research. The purpose is to advance research, establish a research network and to […]

July 29, 2013 Science Blog By David Carlson

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