Science Blog

Effect of R-lipoic Acid in Glaucoma Patients

Abstract Objective: To analyse the safety and effectiveness of the oral administration of a commercialised supplement containing R-alpha lipoic acid, taurine, vitamins C and E, lutein, zeaxanthin, zinc, copper and docosahexaenoic acid, in patients with primary open angle glaucoma (POAG), and in control subjects. Material and methods: A prospective study of cases and controls was […]

June 8, 2020 Science Blog By GeroNova Research

Effects of Alpha Lipoic Acid in Obese Children and Adolescents

Abstract Objectives: Obesity is significantly associated with inflammatory process and oxidative stress. Alpha lipoic acid (ALA) is a potent antioxidant that has been reported for reducing weight in animals and obese adults in several studies but no data are available in pediatrics. We investigated the possible beneficial role of ALA in obese children. Patients and […]

June 3, 2020 Consumer Blog By GeroNova Research

Lipoic Acid a Multi-Level Molecular Inhibitor of Tumorigenesis

Abstract We discuss how lipoic acid (LA), a natural antioxidant, induces apoptosis and inhibits proliferation, EMT, metastasis and stemness of cancer cells. Furthermore, owing to its ability to reduce chemotherapy-induced side effects and chemoresistance, LA appears to be a promising compound for cancer treatment.

June 3, 2020 Consumer Blog By GeroNova Research

Alpha-lipoic Acid Inhibits Lung Cancer Growth

Abstract Lung cancer is the leading cause of cancer-related death, and there remains a need for novel therapies for this malignancy. Here, we examined the effects of alpha-lipoic acid (LA), a drug used for treating human diabetic complications, on lung cancer growth. We report that LA limited lung cancer growth in xenograft mice and reduced […]

June 3, 2020 Science Blog By GeroNova Research

The Use of R-ALA in Patients with Mild-Moderate Carpal Tunnel Syndrome

Abstract Introduction: Carpal tunnel syndrome is one of the most common peripheral neuropathies. Only a few studies evaluate the efficacy of “nutraceuticals” on peripheral nerves and neuropathic pain. The aim of the present investigation is to evaluate the role of R-ALA on clinical and functional outcomes in patients affected by mild to moderate carpal tunnel […]

April 21, 2020 Consumer Blog By GeroNova Research

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