David Carlson is the co-founder and Director of Research & Development GeroNova Research Inc. David has 31 years of experience in organic process chemistry. He is the developer of the GeroNova Research product line and an authority on lipoic acid stereochemistry.
According to Professor Lester Packer, “David is a walking encyclopedia of lipoic acid. He knows as much about lipoic acid as anyone on the planet.”
David gained an academic interest in mechanisms of aging and began exploring the possibility of pharmacological intervention into the aging process in 1998. Animal models indicated R-lipoic acid (RLA) may normalize several age-related markers to those of youthful animals.
RLA was commercially unavailable at that time, so he began to work out industrially feasible routes to produce R-Lipoic Acid and stable-bioavailable dosage forms on a large scale, which evolved into GeroNova Research, Inc. David has played a key role in the introduction and development of R-Lipoic Acid, K-RALA, Na-RALA, Rala-Gel and R-DHLA for the nutraceutical industry.
David’s latest research is the development of entirely “green” and asymmetric processes for the industrial scale synthesis of R-Lipoic Acid and R-DHLA, and the contribution of stereochemistry and the metabolites to the overall mechanisms of action of RLA/R-DHLA. He is continuously testing and developing novel dosage forms, evaluating the plasma pharmacokinetics of R-Lipoic Acid and various nutritional supplements and identifying new biomarkers for quantitation and intervention into the aging process.
GeroNova has compiled an extensive data base of English and foreign language lipoic acid articles and is actively translating foreign articles into English in order to facilitate future researchers. David is actively involved in numerous international collaborations involving the elucidation of the mechanisms of action of R-Lipoic Acid, new product development and clinical trials.
David was an invited speaker at the Oxygen Club of California (OCC) & the Lipoic Acid workshop in Santa Barbara, CA (March 12-15, 2008) where he discussed the pharmacokinetics and pharmacodynamics of R-Lipoic Acid in humans, the role of stereochemistry in the mechanisms of action of lipoic acid and unsolved problems in lipoic acid research. David has spoken at the American College for the Advancement of Medicine, American Association of Naturopathic Physicians (AANP) and Smart Life Forum on the use of R-Lipoic Acid & R-Dihydrolipoic acid in nutrition and clinical practice.
David is a member of The American Chemical Society, The California Academy of Sciences, The New York Academy of Sciences, and the International Union of Pure and Applied Chemistry.